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σ(2)R/TMEM97 in retinal ganglion cell degeneration

The sigma 2 receptor (σ(2)R) was recently identified as an endoplasmic reticulum (ER) membrane protein known as transmembrane protein 97 (TMEM97). Studies have shown that σ(2)R/TMEM97 binding compounds are neuroprotective, suggesting a role of σ(2)R/TMEM97 in neurodegenerative processes. To understa...

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Detalles Bibliográficos
Autores principales:	Wang, Hua, Peng, Zhiyou, Li, Yiwen, Sahn, James J., Hodges, Timothy R., Chou, Tsung-Han, Liu, Qiong, Zhou, Xuezhi, Jiao, Shuliang, Porciatti, Vittorio, Liebl, Daniel J., Martin, Stephen F., Wen, Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715665/ https://www.ncbi.nlm.nih.gov/pubmed/36456686 http://dx.doi.org/10.1038/s41598-022-24537-3

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