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Mycobacterium tuberculosis senses host Interferon-γ via the membrane protein MmpL10

Mycobacterium tuberculosis (Mtb) is one of the most successful human pathogens. Several cytokines are known to increase virulence of bacterial pathogens, leading us to investigate whether Interferon-γ (IFN-γ), a central regulator of the immune defense against Mtb, has a direct effect on the bacteria...

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Detalles Bibliográficos
Autores principales: Ahmed, Mohamed, Mackenzie, Jared, Tezera, Liku, Krause, Robert, Truebody, Barry, Garay-Baquero, Diana, Vallejo, Andres, Govender, Katya, Adamson, John, Fisher, Hayden, Essex, Jonathan W., Mansour, Salah, Elkington, Paul, Steyn, Adrie J. C., Leslie, Alasdair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715692/
https://www.ncbi.nlm.nih.gov/pubmed/36456824
http://dx.doi.org/10.1038/s42003-022-04265-0