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Oligomerization of the heteromeric γ-aminobutyric acid receptor GABA(B) in a eukaryotic cell-free system

Understanding the assembly mechanism and function of membrane proteins is a fundamental problem in biochemical research. Among the membrane proteins, G protein-coupled receptors (GPCRs) represent the largest class in the human body and have long been considered to function as monomers. Nowadays, the...

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Detalles Bibliográficos
Autores principales: Ullrich, Jessica, Göhmann, Philip Jonas, Zemella, Anne, Kubick, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715706/
https://www.ncbi.nlm.nih.gov/pubmed/36456667
http://dx.doi.org/10.1038/s41598-022-24885-0