Enhanced nuclear localization of phosphorylated MLKL predicts adverse events in patients with dilated cardiomyopathy

AIMS: The role of necroptosis in dilated cardiomyopathy (DCM) remains unclear. Here, we examined whether phosphorylation of mixed lineage kinase domain‐like protein (MLKL), an indispensable event for execution of necroptosis, is associated with the progression of DCM. METHODS AND RESULTS: Patients w...

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Detalles Bibliográficos
Autores principales: Fujita, Yugo, Yano, Toshiyuki, Kanamori, Hiromitsu, Nagahara, Daigo, Muranaka, Atsuko, Kouzu, Hidemichi, Mochizuki, Atsushi, Koyama, Masayuki, Nagano, Nobutaka, Fujito, Takefumi, Nishikawa, Ryo, Kamiyama, Naoyuki, Tanaka, Marenao, Kuno, Atsushi, Tanno, Masaya, Miura, Tetsuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715765/
https://www.ncbi.nlm.nih.gov/pubmed/35851586
http://dx.doi.org/10.1002/ehf2.14059

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