Acute changes in systemic glycemia gate access and action of GLP-1R agonist on brain structures controlling energy homeostasis

Therapies based on glucagon-like peptide-1 (GLP-1) long-acting analogs and insulin are often used in the treatment of metabolic diseases. Both insulin and GLP-1 receptors are expressed in metabolically relevant brain regions, suggesting a cooperative action. However, the mechanisms underlying the sy...

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Detalles Bibliográficos
Autores principales: Bakker, Wineke, Imbernon, Monica, Salinas, Casper Gravesen, Moro Chao, Daniela Herrera, Hassouna, Rim, Morel, Chloe, Martin, Claire, Leger, Caroline, Denis, Raphael G.P., Castel, Julien, Peter, Andreas, Heni, Martin, Maetzler, Walter, Nielsen, Heidi Solvang, Duquenne, Manon, Schwaninger, Markus, Lundh, Sofia, Johan Hogendorf, Wouter Frederic, Gangarossa, Giuseppe, Secher, Anna, Hecksher-Sørensen, Jacob, Pedersen, Thomas Åskov, Prevot, Vincent, Luquet, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715912/
https://www.ncbi.nlm.nih.gov/pubmed/36417883
http://dx.doi.org/10.1016/j.celrep.2022.111698

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