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Evolutionary analyses of polymeric immunoglobulin receptor (pIgR) in the mammals reveals an outstanding mutation rate in the lagomorphs

BACKGROUND: The transcytosis of polymeric immunoglobulins, IgA and IgM, across the epithelial barrier to the luminal side of mucosal tissues is mediated by the polymeric immunoglobulin receptor (pIgR). At the luminal side the extracellular ligand binding region of pIgR, the secretory component (SC),...

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Detalles Bibliográficos
Autores principales:	Neves, Fabiana, de Sousa-Pereira, Patrícia, Melo-Ferreira, José, Esteves, Pedro J., Pinheiro, Ana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716071/ https://www.ncbi.nlm.nih.gov/pubmed/36466819 http://dx.doi.org/10.3389/fimmu.2022.1009387

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