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αDβ2 as a novel target of experimental polymicrobial sepsis

Since sepsis was defined three decades ago, it has been a target of intensive study. However, there is no specific sepsis treatment available, with its high mortality and morbidity. αDβ2 (CD11d/CD18) is one of the four β2 integrin members. Its role in sepsis has been limitedly studied. Using an expe...

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Detalles Bibliográficos
Autores principales: Koutsogiannaki, Sophia, Hou, Lifei, Okuno, Toshiaki, Shibamura-Fujiogi, Miho, Luo, Hongbo R., Yuki, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716080/
https://www.ncbi.nlm.nih.gov/pubmed/36466931
http://dx.doi.org/10.3389/fimmu.2022.1059996