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The glucotoxicity protecting effect of honokiol in human hepatocytes via directly activating AMPK

INTRODUCTION: Sustained hyperglycemia causes glucotoxicity, which has been regarded as a contributor to hepatocyte damage in type 2 diabetes (T2D) and its metabolic comorbidities. Honokiol is a natural biphenolic component derived from the dietary supplement Magnolia officinalis extract. This study...

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Detalles Bibliográficos
Autores principales: Liu, Hui, Luo, Wu, Liu, Jiazheng, Kang, Xincong, Yan, Jianming, Zhang, Tingting, Yang, Lan, Shen, Lu, Liu, Dongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716082/
https://www.ncbi.nlm.nih.gov/pubmed/36466390
http://dx.doi.org/10.3389/fnut.2022.1043009

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