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The glucotoxicity protecting effect of honokiol in human hepatocytes via directly activating AMPK
INTRODUCTION: Sustained hyperglycemia causes glucotoxicity, which has been regarded as a contributor to hepatocyte damage in type 2 diabetes (T2D) and its metabolic comorbidities. Honokiol is a natural biphenolic component derived from the dietary supplement Magnolia officinalis extract. This study...
Autores principales: | Liu, Hui, Luo, Wu, Liu, Jiazheng, Kang, Xincong, Yan, Jianming, Zhang, Tingting, Yang, Lan, Shen, Lu, Liu, Dongbo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716082/ https://www.ncbi.nlm.nih.gov/pubmed/36466390 http://dx.doi.org/10.3389/fnut.2022.1043009 |
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