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KLF2 alleviates endothelial cell injury and inhibits the formation of THP‑1 macrophage‑derived foam cells by activating Nrf2 and enhancing autophagy

Atherosclerosis (AS) is an important cause of common vascular diseases. The present study aimed to investigate whether Krüppel like transcription factor 2 (KLF2) could protect against endothelial cell injury and promote cholesterol excretion from foam cells through autophagy. An in vitro AS model wa...

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Detalles Bibliográficos
Autores principales: Tan, Zhen, Ren, Hongqiang, Liu, Yijun, Yang, Hanxuan, Luo, Qian, Deng, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716119/
https://www.ncbi.nlm.nih.gov/pubmed/36478888
http://dx.doi.org/10.3892/etm.2022.11673