An attenuated vaccinia vaccine encoding the severe acute respiratory syndrome coronavirus-2 spike protein elicits broad and durable immune responses, and protects cynomolgus macaques and human angiotensin-converting enzyme 2 transgenic mice from severe acute respiratory syndrome coronavirus-2 and its variants

As long as the coronavirus disease-2019 (COVID-19) pandemic continues, new variants of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) with altered antigenicity will emerge. The development of vaccines that elicit robust, broad, and durable protection against SARS-CoV-2 variants is urge...

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Detalles Bibliográficos
Autores principales: Ishigaki, Hirohito, Yasui, Fumihiko, Nakayama, Misako, Endo, Akinori, Yamamoto, Naoki, Yamaji, Kenzaburo, Nguyen, Cong Thanh, Kitagawa, Yoshinori, Sanada, Takahiro, Honda, Tomoko, Munakata, Tsubasa, Higa, Masahiko, Toyama, Sakiko, Kono, Risa, Takagi, Asako, Matsumoto, Yusuke, Koseki, Aya, Hayashi, Kaori, Shiohara, Masanori, Ishii, Koji, Saeki, Yasushi, Itoh, Yasushi, Kohara, Michinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716133/
https://www.ncbi.nlm.nih.gov/pubmed/36466631
http://dx.doi.org/10.3389/fmicb.2022.967019

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