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ResNet-32 and FastAI for diagnoses of ductal carcinoma from 2D tissue slides

Carcinoma is a primary source of morbidity in women globally, with metastatic disease accounting for most deaths. Its early discovery and diagnosis may significantly increase the odds of survival. Breast cancer imaging is critical for early identification, clinical staging, management choices, and t...

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Autores principales: Praveen, S. Phani, Srinivasu, Parvathaneni Naga, Shafi, Jana, Wozniak, Marcin, Ijaz, Muhammad Fazal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716161/
https://www.ncbi.nlm.nih.gov/pubmed/36460697
http://dx.doi.org/10.1038/s41598-022-25089-2
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author Praveen, S. Phani
Srinivasu, Parvathaneni Naga
Shafi, Jana
Wozniak, Marcin
Ijaz, Muhammad Fazal
author_facet Praveen, S. Phani
Srinivasu, Parvathaneni Naga
Shafi, Jana
Wozniak, Marcin
Ijaz, Muhammad Fazal
author_sort Praveen, S. Phani
collection PubMed
description Carcinoma is a primary source of morbidity in women globally, with metastatic disease accounting for most deaths. Its early discovery and diagnosis may significantly increase the odds of survival. Breast cancer imaging is critical for early identification, clinical staging, management choices, and treatment planning. In the current study, the FastAI technology is used with the ResNet-32 model to precisely identify ductal carcinoma. ResNet-32 is having few layers comparted to majority of its counterparts with almost identical performance. FastAI offers a rapid approximation toward the outcome for deep learning models via GPU acceleration and a faster callback mechanism, which would result in faster execution of the model with lesser code and yield better precision in classifying the tissue slides. Residual Network (ResNet) is proven to handle the vanishing gradient and effective feature learning better. Integration of two computationally efficient technologies has yielded a precision accuracy with reasonable computational efforts. The proposed model has shown considerable efficiency in the evaluating parameters like sensitivity, specificity, accuracy, and F1 Score against the other dominantly used deep learning models. These insights have shown that the proposed approach might assist practitioners in analyzing Breast Cancer (BC) cases appropriately, perhaps saving future complications and death. Clinical and pathological analysis and predictive accuracy have been improved with digital image processing.
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spelling pubmed-97161612022-12-02 ResNet-32 and FastAI for diagnoses of ductal carcinoma from 2D tissue slides Praveen, S. Phani Srinivasu, Parvathaneni Naga Shafi, Jana Wozniak, Marcin Ijaz, Muhammad Fazal Sci Rep Article Carcinoma is a primary source of morbidity in women globally, with metastatic disease accounting for most deaths. Its early discovery and diagnosis may significantly increase the odds of survival. Breast cancer imaging is critical for early identification, clinical staging, management choices, and treatment planning. In the current study, the FastAI technology is used with the ResNet-32 model to precisely identify ductal carcinoma. ResNet-32 is having few layers comparted to majority of its counterparts with almost identical performance. FastAI offers a rapid approximation toward the outcome for deep learning models via GPU acceleration and a faster callback mechanism, which would result in faster execution of the model with lesser code and yield better precision in classifying the tissue slides. Residual Network (ResNet) is proven to handle the vanishing gradient and effective feature learning better. Integration of two computationally efficient technologies has yielded a precision accuracy with reasonable computational efforts. The proposed model has shown considerable efficiency in the evaluating parameters like sensitivity, specificity, accuracy, and F1 Score against the other dominantly used deep learning models. These insights have shown that the proposed approach might assist practitioners in analyzing Breast Cancer (BC) cases appropriately, perhaps saving future complications and death. Clinical and pathological analysis and predictive accuracy have been improved with digital image processing. Nature Publishing Group UK 2022-12-02 /pmc/articles/PMC9716161/ /pubmed/36460697 http://dx.doi.org/10.1038/s41598-022-25089-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Praveen, S. Phani
Srinivasu, Parvathaneni Naga
Shafi, Jana
Wozniak, Marcin
Ijaz, Muhammad Fazal
ResNet-32 and FastAI for diagnoses of ductal carcinoma from 2D tissue slides
title ResNet-32 and FastAI for diagnoses of ductal carcinoma from 2D tissue slides
title_full ResNet-32 and FastAI for diagnoses of ductal carcinoma from 2D tissue slides
title_fullStr ResNet-32 and FastAI for diagnoses of ductal carcinoma from 2D tissue slides
title_full_unstemmed ResNet-32 and FastAI for diagnoses of ductal carcinoma from 2D tissue slides
title_short ResNet-32 and FastAI for diagnoses of ductal carcinoma from 2D tissue slides
title_sort resnet-32 and fastai for diagnoses of ductal carcinoma from 2d tissue slides
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716161/
https://www.ncbi.nlm.nih.gov/pubmed/36460697
http://dx.doi.org/10.1038/s41598-022-25089-2
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