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Functional dynamics of SARS-CoV-2 3C-like protease as a member of clan PA
SARS-CoV-2 3C-like protease (3CL(pro)), a potential therapeutic target for COVID-19, consists of a chymotrypsin fold and a C-terminal α-helical domain (domain III), the latter of which mediates dimerization required for catalytic activation. To gain further understanding of the functional dynamics o...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716165/ https://www.ncbi.nlm.nih.gov/pubmed/36474932 http://dx.doi.org/10.1007/s12551-022-01020-x |