The PI3K inhibitor pictilisib and the multikinase inhibitors pazopanib and sorafenib have an impact on Rac1 level and migration of medulloblastoma in vitro

Metastatic disease is the leading cause of death in children suffering from medulloblastoma and a major treatment challenge. The evidence of leptomeningeal dissemination defines the most aggressive tumours and is associated with increased mortality; thus, inhibition of migration as a factor involved...

Descripción completa

Detalles Bibliográficos
Autores principales: Schoen, Leonie F., Craveiro, Rogerio B., Pietsch, Torsten, Moritz, Thomas, Troeger, Anja, Jordans, Silvia, Dilloo, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716228/
https://www.ncbi.nlm.nih.gov/pubmed/36377725
http://dx.doi.org/10.1111/jcmm.17604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716228/
https://www.ncbi.nlm.nih.gov/pubmed/36377725
http://dx.doi.org/10.1111/jcmm.17604

Ejemplares similares