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Quantitative Spatial Profiling of Immune Populations in Pancreatic Ductal Adenocarcinoma Reveals Tumor Microenvironment Heterogeneity and Prognostic Biomarkers

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive disease with poor 5-year survival rates, necessitating identification of novel therapeutic targets. Elucidating the biology of the tumor immune microenvironment (TiME) can provide vital insights into mechanisms of tumor progression. In t...

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Detalles Bibliográficos
Autores principales: Mi, Haoyang, Sivagnanam, Shamilene, Betts, Courtney B., Liudahl, Shannon M., Jaffee, Elizabeth M., Coussens, Lisa M., Popel, Aleksander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716253/
https://www.ncbi.nlm.nih.gov/pubmed/36112643
http://dx.doi.org/10.1158/0008-5472.CAN-22-1190