Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin

Ovarian carcinosarcoma (OCS) is an aggressive and rare tumor type with limited treatment options. OCS is hypothesized to develop via the combination theory, with a single progenitor resulting in carcinomatous and sarcomatous components, or alternatively via the conversion theory, with the sarcomatou...

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Detalles Bibliográficos
Autores principales: Ho, Gwo Yaw, Kyran, Elizabeth L., Bedo, Justin, Wakefield, Matthew J., Ennis, Darren P., Mirza, Hasan B., Vandenberg, Cassandra J., Lieschke, Elizabeth, Farrell, Andrew, Hadla, Anthony, Lim, Ratana, Dall, Genevieve, Vince, James E., Chua, Ngee Kiat, Kondrashova, Olga, Upstill-Goddard, Rosanna, Bailey, Ulla-Maja, Dowson, Suzanne, Roxburgh, Patricia, Glasspool, Rosalind M., Bryson, Gareth, Biankin, Andrew V., Cooke, Susanna L., Ratnayake, Gayanie, McNally, Orla, Traficante, Nadia, DeFazio, Anna, Weroha, S. John, Bowtell, David D., McNeish, Iain A., Papenfuss, Anthony T., Scott, Clare L., Barker, Holly E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Translational Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716257/
https://www.ncbi.nlm.nih.gov/pubmed/36206301
http://dx.doi.org/10.1158/0008-5472.CAN-21-4012

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