Cargando…

Protective effect of hydroxysafflor yellow A on renal ischemia‑reperfusion injury by targeting the Akt‑Nrf2 axis in mice

Ischemic/reperfusion (I/R) injury is the primary cause of acute kidney injury (AKI). Hydroxysafflor yellow A (HSYA), a natural compound isolated from Carthamus tinctorius L., has been found to possess anti-inflammatory and antioxidant properties. However, the protective effects and potential mechani...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yueming, Han, Kaiyue, Li, Zile, Tang, Xiaoxuan, Wang, Chen, Zhao, Yaxuan, Zhang, Hengchao, Geng, Ziran, Kong, Jie, Luan, Xiying, Xiong, Yanlian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716340/ https://www.ncbi.nlm.nih.gov/pubmed/36478883 http://dx.doi.org/10.3892/etm.2022.11677

Ejemplares similares

hPMSCs-Derived Exosomal miRNA-21 Protects Against Aging-Related Oxidative Damage of CD4(+) T Cells by Targeting the PTEN/PI3K-Nrf2 Axis
por: Xiong, Yanlian, et al.
Publicado: (2021)

Synergistic cardioprotective effects of Danshensu and hydroxysafflor yellow A against myocardial ischemia-reperfusion injury are mediated through the Akt/Nrf2/HO-1 pathway
por: HU, TIANXIN, et al.
Publicado: (2016)

Synergistic cardioprotective effects of Danshensu and hydroxysafflor yellow A against myocardial ischemia-reperfusion injury are mediated through the Akt/Nrf2/HO-1 pathway
por: Hu, Tianxin, et al.
Publicado: (2021)

Hydroxysafflor Yellow A protects spinal cords from ischemia/reperfusion injury in rabbits
por: Shan, Le-qun, et al.
Publicado: (2010)

Hydroxysafflor Yellow A Ameliorates Myocardial Ischemia/Reperfusion Injury by Suppressing Calcium Overload and Apoptosis
por: Ye, Jingxue, et al.
Publicado: (2021)

Synergistic neuroprotective effects of Danshensu and hydroxysafflor yellow A on cerebral ischemia-reperfusion injury in rats
por: Xu, Hang, et al.
Publicado: (2017)

hPMSCs protects against d-galactose-induced oxidative damage of CD4(+) T cells through activating Akt-mediated Nrf2 antioxidant signaling
por: Xiong, Yanlian, et al.
Publicado: (2020)

Hydroxysafflor Yellow A Together with Blood–Brain Barrier Regulator Lexiscan for Cerebral Ischemia Reperfusion Injury Treatment
por: Tan, Liwei, et al.
Publicado: (2020)

Protective potential of hydroxysafflor yellow A in cerebral ischemia and reperfusion injury: An overview of evidence from experimental studies
por: Yu, Lu, et al.
Publicado: (2022)

Hydroxysafflor yellow A alleviates myocardial ischemia/reperfusion in hyperlipidemic animals through the suppression of TLR4 signaling
por: Han, Dan, et al.
Publicado: (2016)

Neuroprotection of hydroxysafflor yellow A in experimental cerebral ischemia/reperfusion injury via metabolic inhibition of phenylalanine and mitochondrial biogenesis
por: Chen, Suning, et al.
Publicado: (2019)

Hydroxysafflor Yellow A mitigated myocardial ischemia/reperfusion injury by inhibiting the activation of the JAK2/STAT1 pathway
por: Zhou, Donglai, et al.
Publicado: (2019)

Hydroxysafflor Yellow A Protects Against Myocardial Ischemia/Reperfusion Injury via Suppressing NLRP3 Inflammasome and Activating Autophagy
por: Ye, Jingxue, et al.
Publicado: (2020)

Hydroxysafflor yellow A improved retinopathy via Nrf2/HO-1 pathway in rats
por: Sun, Zhihui, et al.
Publicado: (2022)

Corrigendum: Hydroxysafflor Yellow A Protects Against Myocardial Ischemia/Reperfusion Injury via Suppressing NLRP3 Inflammasome and Activating Autophagy
por: Ye, Jingxue, et al.
Publicado: (2021)

Hydroxysafflor Yellow A (HSYA) Improves Learning and Memory in Cerebral Ischemia Reperfusion-Injured Rats via Recovering Synaptic Plasticity in the Hippocampus
por: Yu, Lu, et al.
Publicado: (2018)

hPMSCs inhibit the expression of PD-1 in CD4(+)IL-10(+) T cells and mitigate liver damage in a GVHD mouse model by regulating the crosstalk between Nrf2 and NF-κB signaling pathway
por: Zhang, Aiping, et al.
Publicado: (2021)

Establishment of Fluorescence Sensitization Method for Hydroxysafflor Yellow A
por: Haiyan, CAO, et al.
Publicado: (2020)

Nanoemulsions of Hydroxysafflor Yellow A for Enhancing Physicochemical and In Vivo Performance
por: Zhang, Yingjie, et al.
Publicado: (2023)

Therapeutic Potential of Hydroxysafflor Yellow A on Cardio-Cerebrovascular Diseases
por: Bai, Xue, et al.
Publicado: (2020)

Hydroxysafflor Yellow A and Anhydrosafflor Yellow B Protect Against Cerebral Ischemia/Reperfusion Injury by Attenuating Oxidative Stress and Apoptosis via the Silent Information Regulator 1 Signaling Pathway
por: Fangma, Yijia, et al.
Publicado: (2021)

Superior Stability of Hydroxysafflor Yellow A in Xuebijing Injection and the Associated Mechanism
por: Pu, Weiling, et al.
Publicado: (2017)

Oligosaccharide attenuates aging‐related liver dysfunction by activating Nrf2 antioxidant signaling
por: Wang, Yueming, et al.
Publicado: (2020)

Hydroxysafflor yellow A protects against angiotensin II-induced hypertrophy
por: Ni, Bin, et al.
Publicado: (2018)

Mechanism of hydroxysafflor yellow A on acute liver injury based on transcriptomics
por: Hou, Xiangmei, et al.
Publicado: (2022)

Hydroxysafflor Yellow A Attenuates Lipopolysaccharide-Induced Neurotoxicity and Neuroinflammation in Primary Mesencephalic Cultures
por: Wang, Tian, et al.
Publicado: (2018)

Protective effect of hydroxysafflor yellow A on MSCs against senescence induced by d-galactose
por: Song, Xiaoqing, et al.
Publicado: (2022)

Hydroxysafflor Yellow A Protects Neurons From Excitotoxic Death through Inhibition of NMDARs
por: Wang, Xingtao, et al.
Publicado: (2016)

Hydroxysafflor yellow A attenuates the expression of inflammatory cytokines in acute soft tissue injury
por: Dong, Fang, et al.
Publicado: (2017)

Hydroxysafflor Yellow A Alleviates Acute Myocardial Ischemia/Reperfusion Injury in Mice by Inhibiting Ferroptosis via the Activation of the HIF-1α/SLC7A11/GPX4 Signaling Pathway
por: Ge, Chaowen, et al.
Publicado: (2023)

Hydroxysafflor yellow A inhibits the proliferation, migration, and invasion of colorectal cancer cells through the PPARγ/PTEN/Akt signaling pathway
por: Su, Dan, et al.
Publicado: (2021)

Hydroxysafflor yellow A exerts antioxidant effects in a rat model of traumatic brain injury
por: Wang, Yang, et al.
Publicado: (2016)

Hydroxysafflor Yellow A: A Promising Therapeutic Agent for a Broad Spectrum of Diseases
por: Ao, Hui, et al.
Publicado: (2018)

Hydroxysafflor Yellow A Shows Protection against PPARγ Inactivation in Nitrosative Neurons
por: Sun, Li, et al.
Publicado: (2018)

Hydroxysafflor yellow A improves established monocrotaline-induced pulmonary arterial hypertension in rats
por: Han, Xiaotong, et al.
Publicado: (2016)

Protective effect of hydroxysafflor yellow A on cyclosporin A-induced renal oxidative stress in vitro and in vivo
por: Wang, Jiyuan, et al.
Publicado: (2022)

Proteomic investigation of effects of hydroxysafflor yellow A in oxidized low-density lipoprotein-induced endothelial injury
por: Ye, Feng, et al.
Publicado: (2017)

Effects of Hydroxysafflor Yellow A on the PI3K/AKT Pathway and Apoptosis of Pancreatic β-Cells in Type 2 Diabetes Mellitus Rats
por: Lee, Maosheng, et al.
Publicado: (2020)

Enhanced effect and mechanism of water-in-oil microemulsion as an oral delivery system of hydroxysafflor yellow A
por: Qi, Jianping, et al.
Publicado: (2011)

Hydroxysafflor Yellow A Ameliorates Renal Fibrosis by Suppressing TGF-β1-Induced Epithelial-to-Mesenchymal Transition
por: Hu, Naping, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_forjrcgshkbb8r27hnhv8084g5