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Classification and visual explanation for COVID-19 pneumonia from CT images using triple learning

This study presents a novel framework for classifying and visualizing pneumonia induced by COVID-19 from CT images. Although many image classification methods using deep learning have been proposed, in the case of medical image fields, standard classification methods are unable to be used in some ca...

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Autores principales: Kato, Sota, Oda, Masahiro, Mori, Kensaku, Shimizu, Akinobu, Otake, Yoshito, Hashimoto, Masahiro, Akashi, Toshiaki, Hotta, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716499/
https://www.ncbi.nlm.nih.gov/pubmed/36460708
http://dx.doi.org/10.1038/s41598-022-24936-6
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author Kato, Sota
Oda, Masahiro
Mori, Kensaku
Shimizu, Akinobu
Otake, Yoshito
Hashimoto, Masahiro
Akashi, Toshiaki
Hotta, Kazuhiro
author_facet Kato, Sota
Oda, Masahiro
Mori, Kensaku
Shimizu, Akinobu
Otake, Yoshito
Hashimoto, Masahiro
Akashi, Toshiaki
Hotta, Kazuhiro
author_sort Kato, Sota
collection PubMed
description This study presents a novel framework for classifying and visualizing pneumonia induced by COVID-19 from CT images. Although many image classification methods using deep learning have been proposed, in the case of medical image fields, standard classification methods are unable to be used in some cases because the medical images that belong to the same category vary depending on the progression of the symptoms and the size of the inflamed area. In addition, it is essential that the models used be transparent and explainable, allowing health care providers to trust the models and avoid mistakes. In this study, we propose a classification method using contrastive learning and an attention mechanism. Contrastive learning is able to close the distance for images of the same category and generate a better feature space for classification. An attention mechanism is able to emphasize an important area in the image and visualize the location related to classification. Through experiments conducted on two-types of classification using a three-fold cross validation, we confirmed that the classification accuracy was significantly improved; in addition, a detailed visual explanation was achieved comparison with conventional methods.
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spelling pubmed-97164992022-12-02 Classification and visual explanation for COVID-19 pneumonia from CT images using triple learning Kato, Sota Oda, Masahiro Mori, Kensaku Shimizu, Akinobu Otake, Yoshito Hashimoto, Masahiro Akashi, Toshiaki Hotta, Kazuhiro Sci Rep Article This study presents a novel framework for classifying and visualizing pneumonia induced by COVID-19 from CT images. Although many image classification methods using deep learning have been proposed, in the case of medical image fields, standard classification methods are unable to be used in some cases because the medical images that belong to the same category vary depending on the progression of the symptoms and the size of the inflamed area. In addition, it is essential that the models used be transparent and explainable, allowing health care providers to trust the models and avoid mistakes. In this study, we propose a classification method using contrastive learning and an attention mechanism. Contrastive learning is able to close the distance for images of the same category and generate a better feature space for classification. An attention mechanism is able to emphasize an important area in the image and visualize the location related to classification. Through experiments conducted on two-types of classification using a three-fold cross validation, we confirmed that the classification accuracy was significantly improved; in addition, a detailed visual explanation was achieved comparison with conventional methods. Nature Publishing Group UK 2022-12-02 /pmc/articles/PMC9716499/ /pubmed/36460708 http://dx.doi.org/10.1038/s41598-022-24936-6 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Kato, Sota
Oda, Masahiro
Mori, Kensaku
Shimizu, Akinobu
Otake, Yoshito
Hashimoto, Masahiro
Akashi, Toshiaki
Hotta, Kazuhiro
Classification and visual explanation for COVID-19 pneumonia from CT images using triple learning
title Classification and visual explanation for COVID-19 pneumonia from CT images using triple learning
title_full Classification and visual explanation for COVID-19 pneumonia from CT images using triple learning
title_fullStr Classification and visual explanation for COVID-19 pneumonia from CT images using triple learning
title_full_unstemmed Classification and visual explanation for COVID-19 pneumonia from CT images using triple learning
title_short Classification and visual explanation for COVID-19 pneumonia from CT images using triple learning
title_sort classification and visual explanation for covid-19 pneumonia from ct images using triple learning
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716499/
https://www.ncbi.nlm.nih.gov/pubmed/36460708
http://dx.doi.org/10.1038/s41598-022-24936-6
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