Characteristics of the 6th Japanese wave of COVID-19 in hemodialysis patients

BACKGROUND: We examined the clinical characteristics of hemodialysis patients with COVID-19 during the 6th wave of infection (mainly Omicron variant) in Japan. METHODS: Hemodialysis patients admitted in January 2022 and thereafter were grouped as the 6th wave group (n = 53), while others were groupe...

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Autores principales: Haruta, Munenori, Otsubo, Shigeru, Otsubo, Yuriko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716504/
https://www.ncbi.nlm.nih.gov/pubmed/36474652
http://dx.doi.org/10.1186/s41100-022-00451-2
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author Haruta, Munenori
Otsubo, Shigeru
Otsubo, Yuriko
author_facet Haruta, Munenori
Otsubo, Shigeru
Otsubo, Yuriko
author_sort Haruta, Munenori
collection PubMed
description BACKGROUND: We examined the clinical characteristics of hemodialysis patients with COVID-19 during the 6th wave of infection (mainly Omicron variant) in Japan. METHODS: Hemodialysis patients admitted in January 2022 and thereafter were grouped as the 6th wave group (n = 53), while others were grouped as the 1st–5th wave group (n = 47). RESULTS: The proportion of vaccinations was significantly higher in the 6th wave group than in the 1st–5th wave group (96.2% vs 10.6%, p < 0.0001). Neutralizing antibody and molnupiravir were used more frequently in the 6th wave group (75.5% and 88.7%) than in the 1st–5th wave group (14.9% and 0%, both p < 0.0001). The critical disease was seen in 21.3% of the patients in the 1st–5th wave group and 0% in the 6th wave group (p < 0.001). CONCLUSION: The prognosis of hemodialysis patients in the 6th wave group was good. The vaccination and advances in the treatment may have contributed to the outcomes.
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spelling pubmed-97165042022-12-02 Characteristics of the 6th Japanese wave of COVID-19 in hemodialysis patients Haruta, Munenori Otsubo, Shigeru Otsubo, Yuriko Ren Replace Ther Research BACKGROUND: We examined the clinical characteristics of hemodialysis patients with COVID-19 during the 6th wave of infection (mainly Omicron variant) in Japan. METHODS: Hemodialysis patients admitted in January 2022 and thereafter were grouped as the 6th wave group (n = 53), while others were grouped as the 1st–5th wave group (n = 47). RESULTS: The proportion of vaccinations was significantly higher in the 6th wave group than in the 1st–5th wave group (96.2% vs 10.6%, p < 0.0001). Neutralizing antibody and molnupiravir were used more frequently in the 6th wave group (75.5% and 88.7%) than in the 1st–5th wave group (14.9% and 0%, both p < 0.0001). The critical disease was seen in 21.3% of the patients in the 1st–5th wave group and 0% in the 6th wave group (p < 0.001). CONCLUSION: The prognosis of hemodialysis patients in the 6th wave group was good. The vaccination and advances in the treatment may have contributed to the outcomes. BioMed Central 2022-12-02 2022 /pmc/articles/PMC9716504/ /pubmed/36474652 http://dx.doi.org/10.1186/s41100-022-00451-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Haruta, Munenori
Otsubo, Shigeru
Otsubo, Yuriko
Characteristics of the 6th Japanese wave of COVID-19 in hemodialysis patients
title Characteristics of the 6th Japanese wave of COVID-19 in hemodialysis patients
title_full Characteristics of the 6th Japanese wave of COVID-19 in hemodialysis patients
title_fullStr Characteristics of the 6th Japanese wave of COVID-19 in hemodialysis patients
title_full_unstemmed Characteristics of the 6th Japanese wave of COVID-19 in hemodialysis patients
title_short Characteristics of the 6th Japanese wave of COVID-19 in hemodialysis patients
title_sort characteristics of the 6th japanese wave of covid-19 in hemodialysis patients
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716504/
https://www.ncbi.nlm.nih.gov/pubmed/36474652
http://dx.doi.org/10.1186/s41100-022-00451-2
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