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SARS-CoV-2 spike protein induces a differential monocyte activation that may contribute to age bias in COVID-19 severity

A strong bias related to age is observed in COVID-19 patients with pediatric subjects developing a milder disease than adults. We hypothesized that a specific SARS-CoV-2 effect conjugated with preexisting differences in the immune systems may explain this. Using flow cytometry, we investigated basal...

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Detalles Bibliográficos
Autores principales:	Ait-Belkacem, Ines, Cartagena García, Celia, Millet-Wallisky, Ewa, Izquierdo, Nicolas, Loosveld, Marie, Arnoux, Isabelle, Morange, Pierre-Emmanuel, Galland, Franck, Lambert, Nathalie, Malergue, Fabrice, Busnel, Jean-Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716544/ https://www.ncbi.nlm.nih.gov/pubmed/36460710 http://dx.doi.org/10.1038/s41598-022-25259-2

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