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The structure of His-tagged Geobacillus stearothermophilus purine nucleoside phosphorylase reveals a ‘spanner in the works’

The 1.72 Å resolution structure of purine nucleoside phosphorylase from Geobacillus stearothermophilus, a thermostable protein of potential interest for the biocatalytic synthesis of antiviral nucleoside compounds, is reported. The structure of the N-terminally His-tagged enzyme is a hexamer, as is...

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Detalles Bibliográficos
Autores principales:	Given, Fiona M., Moran, Fuchsia, Johns, Ashleigh S., Titterington, James A., Allison, Timothy M., Crittenden, Deborah L., Johnston, Jodie M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2022
Materias:	Research Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716568/ https://www.ncbi.nlm.nih.gov/pubmed/36458621 http://dx.doi.org/10.1107/S2053230X22011025

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