Severe mpox (formerly monkeypox) disease in five patients after recent vaccination with MVA-BN vaccine, Belgium, July to October 2022

Vaccination is important in containing the 2022 mpox (formerly monkeypox) epidemic. We describe five Belgian patients with localised severe symptoms of proctitis and penile oedema, occurring between 4 and 35 days after post-exposure preventive vaccination or after one- or two-dose off-label pre-expo...

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Autores principales: Berens-Riha, Nicole, De Block, Tessa, Rutgers, Jojanneke, Michiels, Johan, Van Gestel, Liesbeth, Hens, Matilde, Kenyon, Chris, Bottieau, Emmanuel, Soentjens, Patrick, van Griensven, Johan, Brosius, Isabel, Ariën, Kevin K, Van Esbroeck, Marjan, Rezende, Antonio Mauro, Vercauteren, Koen, Liesenborghs, Laurens, Van Dijck, Christophe, De Baetselier, Irith, Van den Bossche, Dorien, Florence, Eric, Adriaensen, Wim, Coppens, Jasmine, Vanroye, Fien, Ramadan, Kadrie, Van Looveren, Karin, Baeyens, Jolien, Heyndrickx, Leo, Rasson, Hanne, Verschueren, Jacob, Bracke, Stefanie, Vandenhove, Leen, Vanhamel, Jef, Vuylsteke, Bea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2022
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716643/
https://www.ncbi.nlm.nih.gov/pubmed/36695462
http://dx.doi.org/10.2807/1560-7917.ES.2022.27.48.2200894
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author Berens-Riha, Nicole
De Block, Tessa
Rutgers, Jojanneke
Michiels, Johan
Van Gestel, Liesbeth
Hens, Matilde
Kenyon, Chris
Bottieau, Emmanuel
Soentjens, Patrick
van Griensven, Johan
Brosius, Isabel
Ariën, Kevin K
Van Esbroeck, Marjan
Rezende, Antonio Mauro
Vercauteren, Koen
Liesenborghs, Laurens
Van Dijck, Christophe
De Baetselier, Irith
Van den Bossche, Dorien
Florence, Eric
Adriaensen, Wim
Coppens, Jasmine
Vanroye, Fien
Ramadan, Kadrie
Van Looveren, Karin
Baeyens, Jolien
Heyndrickx, Leo
Rasson, Hanne
Verschueren, Jacob
Bracke, Stefanie
Vandenhove, Leen
Vanhamel, Jef
Vuylsteke, Bea
author_facet Berens-Riha, Nicole
De Block, Tessa
Rutgers, Jojanneke
Michiels, Johan
Van Gestel, Liesbeth
Hens, Matilde
Kenyon, Chris
Bottieau, Emmanuel
Soentjens, Patrick
van Griensven, Johan
Brosius, Isabel
Ariën, Kevin K
Van Esbroeck, Marjan
Rezende, Antonio Mauro
Vercauteren, Koen
Liesenborghs, Laurens
Van Dijck, Christophe
De Baetselier, Irith
Van den Bossche, Dorien
Florence, Eric
Adriaensen, Wim
Coppens, Jasmine
Vanroye, Fien
Ramadan, Kadrie
Van Looveren, Karin
Baeyens, Jolien
Heyndrickx, Leo
Rasson, Hanne
Verschueren, Jacob
Bracke, Stefanie
Vandenhove, Leen
Vanhamel, Jef
Vuylsteke, Bea
author_sort Berens-Riha, Nicole
collection PubMed
description Vaccination is important in containing the 2022 mpox (formerly monkeypox) epidemic. We describe five Belgian patients with localised severe symptoms of proctitis and penile oedema, occurring between 4 and 35 days after post-exposure preventive vaccination or after one- or two-dose off-label pre-exposure preventive vaccination with MVA-BN vaccine. Genome sequencing did not reveal evidence for immune escape variants. Healthcare workers and those at risk should be aware of possible infections occurring shortly after vaccination and the need for other preventive measures.
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spelling pubmed-97166432022-12-12 Severe mpox (formerly monkeypox) disease in five patients after recent vaccination with MVA-BN vaccine, Belgium, July to October 2022 Berens-Riha, Nicole De Block, Tessa Rutgers, Jojanneke Michiels, Johan Van Gestel, Liesbeth Hens, Matilde Kenyon, Chris Bottieau, Emmanuel Soentjens, Patrick van Griensven, Johan Brosius, Isabel Ariën, Kevin K Van Esbroeck, Marjan Rezende, Antonio Mauro Vercauteren, Koen Liesenborghs, Laurens Van Dijck, Christophe De Baetselier, Irith Van den Bossche, Dorien Florence, Eric Adriaensen, Wim Coppens, Jasmine Vanroye, Fien Ramadan, Kadrie Van Looveren, Karin Baeyens, Jolien Heyndrickx, Leo Rasson, Hanne Verschueren, Jacob Bracke, Stefanie Vandenhove, Leen Vanhamel, Jef Vuylsteke, Bea Euro Surveill Rapid Communication Vaccination is important in containing the 2022 mpox (formerly monkeypox) epidemic. We describe five Belgian patients with localised severe symptoms of proctitis and penile oedema, occurring between 4 and 35 days after post-exposure preventive vaccination or after one- or two-dose off-label pre-exposure preventive vaccination with MVA-BN vaccine. Genome sequencing did not reveal evidence for immune escape variants. Healthcare workers and those at risk should be aware of possible infections occurring shortly after vaccination and the need for other preventive measures. European Centre for Disease Prevention and Control (ECDC) 2022-12-01 /pmc/articles/PMC9716643/ /pubmed/36695462 http://dx.doi.org/10.2807/1560-7917.ES.2022.27.48.2200894 Text en This article is copyright of the authors or their affiliated institutions, 2022. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Berens-Riha, Nicole
De Block, Tessa
Rutgers, Jojanneke
Michiels, Johan
Van Gestel, Liesbeth
Hens, Matilde
Kenyon, Chris
Bottieau, Emmanuel
Soentjens, Patrick
van Griensven, Johan
Brosius, Isabel
Ariën, Kevin K
Van Esbroeck, Marjan
Rezende, Antonio Mauro
Vercauteren, Koen
Liesenborghs, Laurens
Van Dijck, Christophe
De Baetselier, Irith
Van den Bossche, Dorien
Florence, Eric
Adriaensen, Wim
Coppens, Jasmine
Vanroye, Fien
Ramadan, Kadrie
Van Looveren, Karin
Baeyens, Jolien
Heyndrickx, Leo
Rasson, Hanne
Verschueren, Jacob
Bracke, Stefanie
Vandenhove, Leen
Vanhamel, Jef
Vuylsteke, Bea
Severe mpox (formerly monkeypox) disease in five patients after recent vaccination with MVA-BN vaccine, Belgium, July to October 2022
title Severe mpox (formerly monkeypox) disease in five patients after recent vaccination with MVA-BN vaccine, Belgium, July to October 2022
title_full Severe mpox (formerly monkeypox) disease in five patients after recent vaccination with MVA-BN vaccine, Belgium, July to October 2022
title_fullStr Severe mpox (formerly monkeypox) disease in five patients after recent vaccination with MVA-BN vaccine, Belgium, July to October 2022
title_full_unstemmed Severe mpox (formerly monkeypox) disease in five patients after recent vaccination with MVA-BN vaccine, Belgium, July to October 2022
title_short Severe mpox (formerly monkeypox) disease in five patients after recent vaccination with MVA-BN vaccine, Belgium, July to October 2022
title_sort severe mpox (formerly monkeypox) disease in five patients after recent vaccination with mva-bn vaccine, belgium, july to october 2022
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716643/
https://www.ncbi.nlm.nih.gov/pubmed/36695462
http://dx.doi.org/10.2807/1560-7917.ES.2022.27.48.2200894
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