Comprehensive microRNA analysis across genome-edited colorectal cancer organoid models reveals miR-24 as a candidate regulator of cell survival

Somatic mutations drive colorectal cancer (CRC) by disrupting gene regulatory mechanisms. Distinct combinations of mutations can result in unique changes to regulatory mechanisms leading to variability in the efficacy of therapeutics. MicroRNAs are important regulators of gene expression, and their...

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Detalles Bibliográficos
Autores principales: Villanueva, Jonathan W., Kwong, Lawrence, Han, Teng, Martinez, Salvador Alonso, Shanahan, Michael T., Kanke, Matt, Dow, Lukas E., Danko, Charles G., Sethupathy, Praveen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716731/
https://www.ncbi.nlm.nih.gov/pubmed/36457077
http://dx.doi.org/10.1186/s12864-022-09018-1

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