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p53 regulates expression of nuclear envelope components in cancer cells
Nuclear organisation and architecture are essential for the maintenance of genomic integrity as well as for the epigenetic regulations and gene expression. Disruption of lamin B1, major structural and functional member of the nuclear lamina, is observed in human laminopathies and in sporadic cancers...
Autores principales: | Panatta, Emanuele, Butera, Alessio, Celardo, Ivana, Leist, Marcel, Melino, Gerry, Amelio, Ivano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716746/ https://www.ncbi.nlm.nih.gov/pubmed/36461070 http://dx.doi.org/10.1186/s13062-022-00349-3 |
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