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Pediatric intestinal obstruction: analysis of etiologies and factors influencing short-term outcomes in Rwanda

BACKGROUND: Intestinal obstruction is a common presentation in pediatric surgical emergencies and presents with different etiologies depending on country or region. Its morbidity and mortality are high in low-income and middle-income countries, with variable influencing factors. The aims of this stu...

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Autores principales: Twahirwa, Isaie, Ndayiragije, Cyriaque, Nyundo, Martin, Rickard, Jennifer, Ntaganda, Edmond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716890/
https://www.ncbi.nlm.nih.gov/pubmed/36474731
http://dx.doi.org/10.1136/wjps-2022-000424
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author Twahirwa, Isaie
Ndayiragije, Cyriaque
Nyundo, Martin
Rickard, Jennifer
Ntaganda, Edmond
author_facet Twahirwa, Isaie
Ndayiragije, Cyriaque
Nyundo, Martin
Rickard, Jennifer
Ntaganda, Edmond
author_sort Twahirwa, Isaie
collection PubMed
description BACKGROUND: Intestinal obstruction is a common presentation in pediatric surgical emergencies and presents with different etiologies depending on country or region. Its morbidity and mortality are high in low-income and middle-income countries, with variable influencing factors. The aims of this study were to determine the etiologies, morbidity and mortality of pediatric intestinal obstruction and to assess the factors associated with the outcomes of these conditions in Rwanda. METHODS: This was a cross-sectional study conducted on pediatric patients with intestinal obstruction in two Rwandan university teaching hospitals. The patients were followed from admission until discharge, and we documented their basic characteristics, diagnosis, operative details and postoperative outcomes. Data were collected using data collection form and were electronically captured and analysed using SPSS software. RESULTS: A total of 65 patients were enrolled in this study. They were predominantly male (n=49, 75.4%), and the majority of patients (86.2%) were below age 6 years. Intussusception was the most common etiology (n=22, 33.8%). Other common etiologies were Hirschsprung’s disease (n=13, 20%), incarcerated inguinal and umbilical hernias (n=6, 9.2%), intestinal worms’ impaction (n=5, 7.7%) and adhesions (n=5, 7.7%). Mortality and morbidity were 9.2% and 39.7%, respectively. The most common complications were surgical site infection (n=6, 9.5%) and sepsis (n=6, 9.5%). Preoperative anemia (p=0.001), finding of gangrenous bowels (p=0.003) and bowel resection at the time of laparotomy (p=0.039) were factors associated with postoperative complications. CONCLUSIONS: The etiologies of intestinal obstruction are variable and common in children below 6 years in Rwanda. The associated morbidly is high and is influenced by the preoperative anemia, finding of gangrenous bowels and bowel resection.
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spelling pubmed-97168902022-12-05 Pediatric intestinal obstruction: analysis of etiologies and factors influencing short-term outcomes in Rwanda Twahirwa, Isaie Ndayiragije, Cyriaque Nyundo, Martin Rickard, Jennifer Ntaganda, Edmond World J Pediatr Surg Original Research BACKGROUND: Intestinal obstruction is a common presentation in pediatric surgical emergencies and presents with different etiologies depending on country or region. Its morbidity and mortality are high in low-income and middle-income countries, with variable influencing factors. The aims of this study were to determine the etiologies, morbidity and mortality of pediatric intestinal obstruction and to assess the factors associated with the outcomes of these conditions in Rwanda. METHODS: This was a cross-sectional study conducted on pediatric patients with intestinal obstruction in two Rwandan university teaching hospitals. The patients were followed from admission until discharge, and we documented their basic characteristics, diagnosis, operative details and postoperative outcomes. Data were collected using data collection form and were electronically captured and analysed using SPSS software. RESULTS: A total of 65 patients were enrolled in this study. They were predominantly male (n=49, 75.4%), and the majority of patients (86.2%) were below age 6 years. Intussusception was the most common etiology (n=22, 33.8%). Other common etiologies were Hirschsprung’s disease (n=13, 20%), incarcerated inguinal and umbilical hernias (n=6, 9.2%), intestinal worms’ impaction (n=5, 7.7%) and adhesions (n=5, 7.7%). Mortality and morbidity were 9.2% and 39.7%, respectively. The most common complications were surgical site infection (n=6, 9.5%) and sepsis (n=6, 9.5%). Preoperative anemia (p=0.001), finding of gangrenous bowels (p=0.003) and bowel resection at the time of laparotomy (p=0.039) were factors associated with postoperative complications. CONCLUSIONS: The etiologies of intestinal obstruction are variable and common in children below 6 years in Rwanda. The associated morbidly is high and is influenced by the preoperative anemia, finding of gangrenous bowels and bowel resection. BMJ Publishing Group 2022-10-31 /pmc/articles/PMC9716890/ /pubmed/36474731 http://dx.doi.org/10.1136/wjps-2022-000424 Text en © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Original Research
Twahirwa, Isaie
Ndayiragije, Cyriaque
Nyundo, Martin
Rickard, Jennifer
Ntaganda, Edmond
Pediatric intestinal obstruction: analysis of etiologies and factors influencing short-term outcomes in Rwanda
title Pediatric intestinal obstruction: analysis of etiologies and factors influencing short-term outcomes in Rwanda
title_full Pediatric intestinal obstruction: analysis of etiologies and factors influencing short-term outcomes in Rwanda
title_fullStr Pediatric intestinal obstruction: analysis of etiologies and factors influencing short-term outcomes in Rwanda
title_full_unstemmed Pediatric intestinal obstruction: analysis of etiologies and factors influencing short-term outcomes in Rwanda
title_short Pediatric intestinal obstruction: analysis of etiologies and factors influencing short-term outcomes in Rwanda
title_sort pediatric intestinal obstruction: analysis of etiologies and factors influencing short-term outcomes in rwanda
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716890/
https://www.ncbi.nlm.nih.gov/pubmed/36474731
http://dx.doi.org/10.1136/wjps-2022-000424
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