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Macrophage–NLRP3 Activation Promotes Right Ventricle Failure in Pulmonary Arterial Hypertension

RATIONALE: Pulmonary arterial hypertension (PAH) often results in death from right ventricular failure (RVF). NLRP3 (nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3)-macrophage activation may promote RVF in PAH. OBJECTIVES: Evaluating the contribution of the NLRP...

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Detalles Bibliográficos
Autores principales:	Al-Qazazi, Ruaa, Lima, Patricia D. A., Prisco, Sasha Z., Potus, Francois, Dasgupta, Asish, Chen, Kuang-Hueih, Tian, Lian, Bentley, Rachel E. T., Mewburn, Jeff, Martin, Ashley Y., Wu, Danchen, Jones, Oliver, Maurice, Donald H., Bonnet, Sebastien, Provencher, Steeve, Prins, Kurt W., Archer, Stephen L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Thoracic Society 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716901/ https://www.ncbi.nlm.nih.gov/pubmed/35699679 http://dx.doi.org/10.1164/rccm.202110-2274OC

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