Rechallenge of immune checkpoint inhibitors in a case with adverse events inducing myasthenia gravis

The mechanism(s) of immune checkpoint inhibitor (ICI)-induced myasthenia gravis (MG), an immune-related adverse event (irAE) that is fatal and limits subsequent ICI use, remain unexplored. Here, through comparative genomic analysis, we identified a pathogenic p.S467C germline variant in SLC22A5 in a...

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Detalles Bibliográficos
Autores principales: Gao, Wen, Wu, Lingxiang, Jin, Shidai, Li, Jun, Liu, Xinyin, Xu, Jiali, Zhang, Wei, Gong, Qixing, Sun, Chunxiao, Wang, Wei, Wang, Zidun, Shao, Yang W, Yin, Jiani C, Shen, Lu, Chen, Liang, Wang, Qianghu, Guo, Renhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716945/
https://www.ncbi.nlm.nih.gov/pubmed/36450378
http://dx.doi.org/10.1136/jitc-2022-005970

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