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Mitochondrial toxicants in Xian-Ling-Gu-Bao induce liver injury by regulating the PI3K/mTOR signaling pathway: an in vitro study

BACKGROUND: Drug-induced mitochondrial toxicity is thought to be a common mechanism of drug hepatotoxicity. Xian-Ling-Gu-Bao (XLGB) oral preparation is a commonly used drug for osteoporosis in China. Classical safety evaluation studies have shown that the entire preparation and six Chinese herbal me...

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Detalles Bibliográficos
Autores principales: Piao, Shujuan, Lin, Hongwei, Tao, Xia, Chen, Wansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716976/
https://www.ncbi.nlm.nih.gov/pubmed/36457007
http://dx.doi.org/10.1186/s12906-022-03798-5

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