Cargando…
Phase II clinical and immune correlate study of adjuvant nivolumab plus ipilimumab for high-risk resected melanoma
BACKGROUND: Adjuvant therapy for high-risk resected melanoma with programmed cell-death 1 blockade results in a median relapse-free survival (RFS) of 5 years. The addition of low dose ipilimumab (IPI) to a regimen of adjuvant nivolumab (NIVO) in CheckMate-915 did not result in increased RFS. A pilot...
Autores principales: | Khushalani, Nikhil I, Vassallo, Melinda, Goldberg, Judith D, Eroglu, Zeynep, Kim, Younchul, Cao, Biwei, Ferguson, Robert, Monson, Kelsey R, Kirchhoff, Tomas, Amato, Carol M, Burke, Paulo, Strange, Ann, Monk, Emily, Gibney, Geoffrey Thomas, Kudchadkar, Ragini, Markowitz, Joseph, Brohl, Andrew S, Pavlick, Anna, Richards, Alison, Woods, David M, Weber, Jeffrey |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9717375/ https://www.ncbi.nlm.nih.gov/pubmed/36450385 http://dx.doi.org/10.1136/jitc-2022-005684 |
Ejemplares similares
-
A phase IB study of ipilimumab with peginterferon alfa-2b in patients with unresectable melanoma
por: Brohl, Andrew S., et al.
Publicado: (2016) -
Risks and benefits of reinduction ipilimumab/nivolumab in melanoma patients previously treated with ipilimumab/nivolumab
por: Chapman, Paul B, et al.
Publicado: (2021) -
Evaluation of tissue- and plasma-derived tumor mutational burden (TMB) and genomic alterations of interest in CheckMate 848, a study of nivolumab combined with ipilimumab and nivolumab alone in patients with advanced or metastatic solid tumors with high TMB
por: He, Jie, et al.
Publicado: (2023) -
Ipilimumab plus nivolumab for patients with metastatic uveal melanoma: a multicenter, retrospective study
por: Najjar, Yana G, et al.
Publicado: (2020) -
Biomarker analysis from CheckMate 214: nivolumab plus ipilimumab versus sunitinib in renal cell carcinoma
por: Motzer, Robert J, et al.
Publicado: (2022)