Cargando…

Timing in antibiotic therapy: when and how to start, de-escalate and stop antibiotic therapy. Proposals from a stablished antimicrobial stewardship program

The current morbimortality of serious infections is unacceptable and there is a need to promote the increase in the efficacy of empirical and targeted antibiotherapy. This could be achieved by initiatives coming from ASP teams aimed at promoting increased efficacy of antibiotic therapy .In the optim...

Descripción completa

Detalles Bibliográficos
Autores principales: Pasquau-Liaño, Juan, Sadyrbaeva-Dolgova, Svetlana, Sequera-Arquellada, Sergio, García-Vallecillos, Coral, Hidalgo-Tenorio, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedad Española de Quimioterapia 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9717451/
https://www.ncbi.nlm.nih.gov/pubmed/36285869
http://dx.doi.org/10.37201/req/s03.22.2022
Descripción
Sumario:The current morbimortality of serious infections is unacceptable and there is a need to promote the increase in the efficacy of empirical and targeted antibiotherapy. This could be achieved by initiatives coming from ASP teams aimed at promoting increased efficacy of antibiotic therapy .In the optimization of the antibiotic therapy there are sev eral critical points in which an adequate timing could achieve benefits in the survival of patients with severe infections: prompt initiation of empirical treatment; de-escalation performance, appropriate targeted treatment; and finally, curtail antibiotic duration.