Management of hyperinflammation in COVID-19 patients

In response to SARS-CoV-2 infection, the immune system physiologically upregulates to try to clear the virus from the body; failure to compensate for this inflammatory response with an anti-inflammatory response leads to dysregulation of the immune system that ultimately leads to a situation of unco...

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Detalles Bibliográficos
Autores principales: Suberviola, Borja, Fito, Elena Cuenca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedad Española de Quimioterapia 2022
Materias:
Approach to management of SARS-CoV-2 infection
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9717453/
https://www.ncbi.nlm.nih.gov/pubmed/36285849
http://dx.doi.org/10.37201/req/s03.02.2022
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author Suberviola, Borja
Fito, Elena Cuenca
author_facet Suberviola, Borja
Fito, Elena Cuenca
author_sort Suberviola, Borja
collection PubMed
description In response to SARS-CoV-2 infection, the immune system physiologically upregulates to try to clear the virus from the body; failure to compensate for this inflammatory response with an anti-inflammatory response leads to dysregulation of the immune system that ultimately leads to a situation of uncontrolled hyperinflammation called cytokine storm. This cytokine storm can cause ARDS or multi-organ failure leading to patient death. This review exposes the different mechanisms of the inflammatory response in COVID-19 infection and the therapeutic options to treat this process.
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spelling pubmed-97174532022-12-08 Management of hyperinflammation in COVID-19 patients Suberviola, Borja Fito, Elena Cuenca Rev Esp Quimioter Approach to management of SARS-CoV-2 infection In response to SARS-CoV-2 infection, the immune system physiologically upregulates to try to clear the virus from the body; failure to compensate for this inflammatory response with an anti-inflammatory response leads to dysregulation of the immune system that ultimately leads to a situation of uncontrolled hyperinflammation called cytokine storm. This cytokine storm can cause ARDS or multi-organ failure leading to patient death. This review exposes the different mechanisms of the inflammatory response in COVID-19 infection and the therapeutic options to treat this process. Sociedad Española de Quimioterapia 2022-10-24 2022 /pmc/articles/PMC9717453/ /pubmed/36285849 http://dx.doi.org/10.37201/req/s03.02.2022 Text en © The Author 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)(https://creativecommons.org/licenses/by-nc/4.0/).
spellingShingle Approach to management of SARS-CoV-2 infection
Suberviola, Borja
Fito, Elena Cuenca
Management of hyperinflammation in COVID-19 patients
title Management of hyperinflammation in COVID-19 patients
title_full Management of hyperinflammation in COVID-19 patients
title_fullStr Management of hyperinflammation in COVID-19 patients
title_full_unstemmed Management of hyperinflammation in COVID-19 patients
title_short Management of hyperinflammation in COVID-19 patients
title_sort management of hyperinflammation in covid-19 patients
topic Approach to management of SARS-CoV-2 infection
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9717453/
https://www.ncbi.nlm.nih.gov/pubmed/36285849
http://dx.doi.org/10.37201/req/s03.02.2022
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