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Single low-dose INC280-loaded theranostic nanoparticles achieve multirooted delivery for MET-targeted primary and liver metastatic NSCLC

BACKGROUND: Non-small cell lung cancer (NSCLC) patients with primary tumors and liver metastases have substantially reduced survival. Since mesenchymal-epithelial transition factor (MET) plays a significant role in the molecular mechanisms of advanced NSCLC, small molecule MET inhibitor capmatinib (...

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Detalles Bibliográficos
Autores principales: Sun, Yige, Yang, Jie, Li, Yingbo, Luo, Jing, Sun, Jiemei, Li, Daoshuang, Wang, Yuchen, Wang, Kai, Yang, Lili, Wu, Lina, Sun, Xilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9717478/
https://www.ncbi.nlm.nih.gov/pubmed/36457016
http://dx.doi.org/10.1186/s12943-022-01681-y