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Validated HPLC–PDA methodology utilized for simultaneous determination of Etoricoxib and Paracetamol in the presence of Paracetamol toxic impurities

Etoricoxib (ETO), Paracetamol (PCM), and two toxic impurities for Paracetamol impurity K (4-aminophenol (PAP)) and impurity E (para-hydroxy acetophenone (PHA)) were separated using a simple and selective HPLC method that was tested for the first time. PCM is a commonly used analgesic and antipyretic...

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Detalles Bibliográficos
Autores principales: Abdel Rahman, Mona A., Elghobashy, Mohamed R., Zaazaa, Hala E., Atty, Shimaa A., El-Mosallamy, Sally S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9717564/
https://www.ncbi.nlm.nih.gov/pubmed/36461095
http://dx.doi.org/10.1186/s13065-022-00904-z