Cargando…

Innovative Approaches for Breast Cancer Metastasis to the Brain

Breast cancer metastasis is a continued concern for patients with recent development in our understanding of disease progression. In this paper, we highlight the pathophysiology behind breast cancer metastasis. Blood brain barrier disruption plays a critical component in progression. We then investi...

Descripción completa

Detalles Bibliográficos
Autores principales: Klaas, Elizabeth, Mohamed, Shahd, Poe, Jordan, Reddy, Ramya, Dagra, Abeer, Lucke-Wold, Brandon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9717593/
https://www.ncbi.nlm.nih.gov/pubmed/36468085
http://dx.doi.org/10.31579/2692-9392/147
_version_ 1784842933150679040
author Klaas, Elizabeth
Mohamed, Shahd
Poe, Jordan
Reddy, Ramya
Dagra, Abeer
Lucke-Wold, Brandon
author_facet Klaas, Elizabeth
Mohamed, Shahd
Poe, Jordan
Reddy, Ramya
Dagra, Abeer
Lucke-Wold, Brandon
author_sort Klaas, Elizabeth
collection PubMed
description Breast cancer metastasis is a continued concern for patients with recent development in our understanding of disease progression. In this paper, we highlight the pathophysiology behind breast cancer metastasis. Blood brain barrier disruption plays a critical component in progression. We then investigate the current treatment strategies and recommended guidelines. This focuses on radiation and medical management. Finally, we address the role of surgical intervention. The data is organized into tables and figures to highlight key components. Finally, we address emerging treatments and pre-clinical data. The paper will serve as a user-friendly guide for clinicians and researchers to help formulate a strategy to manage breast cancer metastasis patients sufficiently.
format Online
Article
Text
id pubmed-9717593
institution National Center for Biotechnology Information
language English
publishDate 2022
record_format MEDLINE/PubMed
spelling pubmed-97175932022-12-02 Innovative Approaches for Breast Cancer Metastasis to the Brain Klaas, Elizabeth Mohamed, Shahd Poe, Jordan Reddy, Ramya Dagra, Abeer Lucke-Wold, Brandon Arch Med Case Rep Case Study Article Breast cancer metastasis is a continued concern for patients with recent development in our understanding of disease progression. In this paper, we highlight the pathophysiology behind breast cancer metastasis. Blood brain barrier disruption plays a critical component in progression. We then investigate the current treatment strategies and recommended guidelines. This focuses on radiation and medical management. Finally, we address the role of surgical intervention. The data is organized into tables and figures to highlight key components. Finally, we address emerging treatments and pre-clinical data. The paper will serve as a user-friendly guide for clinicians and researchers to help formulate a strategy to manage breast cancer metastasis patients sufficiently. 2022-10-31 2022-09-22 /pmc/articles/PMC9717593/ /pubmed/36468085 http://dx.doi.org/10.31579/2692-9392/147 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Article
Klaas, Elizabeth
Mohamed, Shahd
Poe, Jordan
Reddy, Ramya
Dagra, Abeer
Lucke-Wold, Brandon
Innovative Approaches for Breast Cancer Metastasis to the Brain
title Innovative Approaches for Breast Cancer Metastasis to the Brain
title_full Innovative Approaches for Breast Cancer Metastasis to the Brain
title_fullStr Innovative Approaches for Breast Cancer Metastasis to the Brain
title_full_unstemmed Innovative Approaches for Breast Cancer Metastasis to the Brain
title_short Innovative Approaches for Breast Cancer Metastasis to the Brain
title_sort innovative approaches for breast cancer metastasis to the brain
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9717593/
https://www.ncbi.nlm.nih.gov/pubmed/36468085
http://dx.doi.org/10.31579/2692-9392/147
work_keys_str_mv AT klaaselizabeth innovativeapproachesforbreastcancermetastasistothebrain
AT mohamedshahd innovativeapproachesforbreastcancermetastasistothebrain
AT poejordan innovativeapproachesforbreastcancermetastasistothebrain
AT reddyramya innovativeapproachesforbreastcancermetastasistothebrain
AT dagraabeer innovativeapproachesforbreastcancermetastasistothebrain
AT luckewoldbrandon innovativeapproachesforbreastcancermetastasistothebrain