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Substrate Specificity and Kinetics of RNA Hydrolysis by SARS-CoV-2 NSP10/14 Exonuclease

[Image: see text] Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the virus that causes COVID-19, continues to evolve resistance to vaccines and existing antiviral therapies at an alarming rate, increasing the need for new direct-acting antiviral drugs. Despite significant advances in...

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Detalles Bibliográficos
Autores principales: Dangerfield, Tyler L., Johnson, Kenneth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718090/
https://www.ncbi.nlm.nih.gov/pubmed/36570070
http://dx.doi.org/10.1021/acsbiomedchemau.2c00046