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TRPV4 activation enhances compressive properties and glycosaminoglycan deposition of equine neocartilage sheets

OBJECTIVE: To evaluate the effect of Transient Receptor Potential Vanilloid 4 (TRPV4) cation channel modulation on mesenchymal stromal cell (MSC)-derived neocartilage. METHODS: RT-PCR was performed to evaluate mRNA levels of chondrogenic, hypertrophic and candidate mechanoresponsive genes in equine...

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Detalles Bibliográficos
Autores principales:	López-Jiménez, Cristóbal, Chiu, Loraine L.Y., Waldman, Stephen D., Guilak, Farshid, Koch, Thomas G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	ORIGINAL PAPER
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718125/ https://www.ncbi.nlm.nih.gov/pubmed/36475280 http://dx.doi.org/10.1016/j.ocarto.2022.100263

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