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Clinical outcome is significantly better with spheroid-based autologous chondrocyte implantation manufactured with more stringent cell culture criteria

OBJECTIVE: Spherox (CO.DON AG) is an autologous chondrocyte implantation (ACI) product, consisting of spheroids of human autologous matrix-associated chondrocytes. The tendency of primary chondrocytes to dedifferentiate during cultivation and the high biologic variability caused by the autologous na...

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Detalles Bibliográficos
Autores principales:	Eschen, C., Kaps, C., Widuchowski, W., Fickert, S., Zinser, W., Niemeyer, Ph, Roël, G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718150/ https://www.ncbi.nlm.nih.gov/pubmed/36474562 http://dx.doi.org/10.1016/j.ocarto.2020.100033

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