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A serological type II collagen neoepitope biomarker reflects cartilage breakdown in patients with osteoarthritis

OBJECTIVES: There is an unmet medical need for biomarkers in OA which can be applied in clinical drug development trials. The present study describes the development of a specific and robust assay measuring type II collagen degradation (T2CM) and discusses its potential as a noninvasive translationa...

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Detalles Bibliográficos
Autores principales:	Groen, Solveig Skovlund, Sinkeviciute, Dovile, Bay-Jensen, Anne-Christine, Thudium, Christian S., Karsdal, Morten A., Thomsen, Simon Francis, Lindemann, Sven, Werkmann, Daniela, Blair, Joseph, Staunstrup, Line Mærsk, Önnerfjord, Patrik, Arendt-Nielsen, Lars, Nielsen, Signe Holm
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	ORIGINAL PAPER
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718155/ https://www.ncbi.nlm.nih.gov/pubmed/36474766 http://dx.doi.org/10.1016/j.ocarto.2021.100207

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