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Inhibition of transforming growth factor-β in osteoarthritis. Discrepancy with reduced TGFβ signaling in normal joints

OBJECTIVE: Transforming growth factor-β (TGFβ) is a pleiotropic cytokine that is central in the regulation of joint health and disease. Inhibition of TGFβ activity/signaling in experimental osteoarthritis (OA) has been performed to modulate OA severity and progression. In this narrative review we di...

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Detalles Bibliográficos
Autor principal: van der Kraan, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718219/
https://www.ncbi.nlm.nih.gov/pubmed/36474474
http://dx.doi.org/10.1016/j.ocarto.2022.100238

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