A human in vitro 3D neo-cartilage model to explore the response of OA risk genes to hyper-physiological mechanical stress

OBJECTIVE: Due to the complexity and heterogeneity of osteoarthritis (OA) pathophysiology, studying the interaction between intrinsic molecular changes in chondrocytes after hyper-physiological mechanical stress (MS) and aberrant signalling of OA risk genes remains a challenge. In this study we set...

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Detalles Bibliográficos
Autores principales: Timmermans, Ritchie G.M., Bloks, Niek G.C., Tuerlings, Margo, van Hoolwerff, Marcella, Nelissen, Rob G.H.H., van der Wal, Robert J.P., van der Kraan, Peter M., Blom, Arjen B., van den Bosch, Martijn H.J., Ramos, Yolande F.M., Meulenbelt, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
BRIEF REPORT(S)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718246/
https://www.ncbi.nlm.nih.gov/pubmed/36474468
http://dx.doi.org/10.1016/j.ocarto.2021.100231

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