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Identifying small molecules for protecting chondrocyte function and matrix integrity after controlled compressive injury

OBJECTIVE: Articular cartilage injury is central for the development of post-traumatic osteoarthritis (PTOA). With few disease-modifying therapies successful at offsetting progressive osteoarthritis (OA), our goal is to use a high throughput screening platform of cartilage injury to identify novel c...

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Detalles Bibliográficos
Autores principales: Al Jundi, Saleh, Martinez, Jerahme R., Cresta, Jake, Yousefi, Farzad, DeSantis, Gabriel, Thoonkuzhy, Matthew, Rabut, Emilie, Mohanraj, Bhavana, Mauck, Robert L., Dodge, George R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718264/
https://www.ncbi.nlm.nih.gov/pubmed/36474951
http://dx.doi.org/10.1016/j.ocarto.2022.100289