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Tissue distribution of sprifermin (recombinant human fibroblast growth factor 18) in the rat following intravenous and intra-articular injection

OBJECTIVE: Fibroblast growth factor 18 (FGF18) is involved in chondrogenesis and articular cartilage repair. We investigated tissue distribution and pharmacokinetics of radioactive [(3)H]sprifermin, a recombinant human FGF18, in rats after a single intravenous (i.v.) or intra-articular (i.a.) inject...

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Detalles Bibliográficos
Autores principales:	Ladel, C.H., Barbero, L., Riva, S., Guehring, H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	ORIGINAL PAPER
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718268/ https://www.ncbi.nlm.nih.gov/pubmed/36474684 http://dx.doi.org/10.1016/j.ocarto.2020.100068

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