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Safety and pharmacokinetics of EP-104IAR (sustained-release fluticasone propionate) in knee osteoarthritis: A randomized, double-blind, placebo-controlled phase 1 trial

OBJECTIVE: EP-104IAR is a novel, sustained-release, intra-articular (IA) formulation of the corticosteroid fluticasone propionate (FP), in development for the treatment of osteoarthritis (OA) pain. This study evaluated the safety, pharmacokinetics (PK) and efficacy of a single dose of EP-104IAR in p...

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Detalles Bibliográficos
Autores principales:	Malone, Amanda, Price, James, Price, Nicola, Peck, Vik, Getgood, Alan, Petrella, Robert, Helliwell, James
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Clinical Trial
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718298/ https://www.ncbi.nlm.nih.gov/pubmed/36474755 http://dx.doi.org/10.1016/j.ocarto.2021.100213

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