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Glucose metabolism is upregulated in the mononuclear cell proteome during sepsis and supports endotoxin-tolerant cell function

Metabolic adaptations shape immune cell function. In the acute response, a metabolic switch towards glycolysis is necessary for mounting a proinflammatory response. During the clinical course of sepsis, both suppression and activation of immune responses take place simultaneously. Leukocytes from se...

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Detalles Bibliográficos
Autores principales: Ferreira, Bianca Lima, Sousa, Mônica Bragança, Leite, Giuseppe Gianini Figueirêdo, Brunialti, Milena Karina Colo, Nishiduka, Erika Sayuri, Tashima, Alexandre Keiji, van der Poll, Tom, Salomão, Reinaldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718365/
https://www.ncbi.nlm.nih.gov/pubmed/36466921
http://dx.doi.org/10.3389/fimmu.2022.1051514