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The apparent interferon resistance of transmitted HIV-1 is possibly a consequence of enhanced replicative fitness

HIV-1 transmission via sexual exposure is an inefficient process. When transmission does occur, newly infected individuals are colonized by the descendants of either a single virion or a very small number of establishing virions. These transmitted founder (TF) viruses are more interferon (IFN)-resis...

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Detalles Bibliográficos
Autores principales: Sugrue, Elena, Wickenhagen, Arthur, Mollentze, Nardus, Aziz, Muhamad Afiq, Sreenu, Vattipally B., Truxa, Sven, Tong, Lily, da Silva Filipe, Ana, Robertson, David L., Hughes, Joseph, Rihn, Suzannah J., Wilson, Sam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718408/
https://www.ncbi.nlm.nih.gov/pubmed/36399512
http://dx.doi.org/10.1371/journal.ppat.1010973