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The apparent interferon resistance of transmitted HIV-1 is possibly a consequence of enhanced replicative fitness
HIV-1 transmission via sexual exposure is an inefficient process. When transmission does occur, newly infected individuals are colonized by the descendants of either a single virion or a very small number of establishing virions. These transmitted founder (TF) viruses are more interferon (IFN)-resis...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718408/ https://www.ncbi.nlm.nih.gov/pubmed/36399512 http://dx.doi.org/10.1371/journal.ppat.1010973 |