Combinations of Host- and Virus-Targeting Antiviral Drugs Confer Synergistic Suppression of SARS-CoV-2

Three directly acting antivirals (DAAs) demonstrated substantial reduction in COVID-19 hospitalizations and deaths in clinical trials. However, these agents did not completely prevent severe illness and are associated with cases of rebound illness and viral shedding. Combination regimens can enhance...

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Detalles Bibliográficos
Autores principales: Wagoner, Jessica, Herring, Shawn, Hsiang, Tien-Ying, Ianevski, Aleksandr, Biering, Scott B., Xu, Shuang, Hoffmann, Markus, Pöhlmann, Stefan, Gale, Michael, Aittokallio, Tero, Schiffer, Joshua T., White, Judith M., Polyak, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718484/
https://www.ncbi.nlm.nih.gov/pubmed/36190406
http://dx.doi.org/10.1128/spectrum.03331-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718484/
https://www.ncbi.nlm.nih.gov/pubmed/36190406
http://dx.doi.org/10.1128/spectrum.03331-22

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