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A role for EMT in CD73 regulation in breast cancer

CD73 is an emerging target in cancer due to its role in generating adenosine, a potent immunosuppressor. We found that SNAI1, a driver of epithelial-to-mesenchymal transition (EMT), upregulates CD73 in triple negative breast cancer cells. Here, we discuss the relevance of improving CD73-based therap...

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Detalles Bibliográficos
Autores principales: Hasmim, Meriem, Berchem, Guy, Janji, Bassam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718558/
https://www.ncbi.nlm.nih.gov/pubmed/36465484
http://dx.doi.org/10.1080/2162402X.2022.2152636