Cargando…

A novel technique for the treatment of radiation-induced acquired esophageal atresia in patients with head and neck cancer

BACKGROUND AND AIMS: Dysphagia is a common complaint for patients after radiation therapy for head and neck cancer. Chronic dysphagia ensues when the radiation-induced injury matures into a fibrotic stricture, with the severity of symptoms paralleling the degree of stenosis. Most patients experience...

Descripción completa

Detalles Bibliográficos
Autores principales: Brindise, Elizabeth, Ashat, Munish, Gerke, Henning, El Abiad, Rami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718655/
https://www.ncbi.nlm.nih.gov/pubmed/36467535
http://dx.doi.org/10.1016/j.vgie.2022.08.003
_version_ 1784843136185401344
author Brindise, Elizabeth
Ashat, Munish
Gerke, Henning
El Abiad, Rami
author_facet Brindise, Elizabeth
Ashat, Munish
Gerke, Henning
El Abiad, Rami
author_sort Brindise, Elizabeth
collection PubMed
description BACKGROUND AND AIMS: Dysphagia is a common complaint for patients after radiation therapy for head and neck cancer. Chronic dysphagia ensues when the radiation-induced injury matures into a fibrotic stricture, with the severity of symptoms paralleling the degree of stenosis. Most patients experience progressive dysphagia that prompts medical attention before complete esophageal obliteration. Rarely, patients present late with inability to clear their secretions because of complete obstruction, also termed acquired atresia. These patients represent a challenge and require aggressive and unconventional interventions to reestablish lumenal patency. Using a case series, we hereby describe a novel yet simple technique to treat patients with acquired esophageal atresia. METHODS: Five patients with head and neck cancer in various stages who all underwent nonsurgical treatment with definitive chemotherapy and radiation along with enteral feeding tube placement prior to/during treatment presented with acquired esophageal atresia. All patients underwent an EGD to reestablish lumenal patency. This was accomplished with gentle pressure that was applied in a to-and-fro semi-circular rotational manner as if pushing a corkscrew and twisting it in alternating clockwise and counterclockwise manner. RESULTS: In all cases we were able to reestablish esophageal lumenal patency with a single procedure. There were no adverse events. Four of the 5 patients required additional dilations for symptomatic management. However, all patients’ esophageal lumens remained patent. CONCLUSIONS: We describe a novel yet simple technique to treat acquired esophageal atresia after radiation for head and neck cancer. This technique allows for generous dilation yielding complete resolution of the stenosis in a single session. When our approach is used, the patient can be discharged home the same day and resume immediate oral intake.
format Online
Article
Text
id pubmed-9718655
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-97186552022-12-03 A novel technique for the treatment of radiation-induced acquired esophageal atresia in patients with head and neck cancer Brindise, Elizabeth Ashat, Munish Gerke, Henning El Abiad, Rami VideoGIE Video Case Series BACKGROUND AND AIMS: Dysphagia is a common complaint for patients after radiation therapy for head and neck cancer. Chronic dysphagia ensues when the radiation-induced injury matures into a fibrotic stricture, with the severity of symptoms paralleling the degree of stenosis. Most patients experience progressive dysphagia that prompts medical attention before complete esophageal obliteration. Rarely, patients present late with inability to clear their secretions because of complete obstruction, also termed acquired atresia. These patients represent a challenge and require aggressive and unconventional interventions to reestablish lumenal patency. Using a case series, we hereby describe a novel yet simple technique to treat patients with acquired esophageal atresia. METHODS: Five patients with head and neck cancer in various stages who all underwent nonsurgical treatment with definitive chemotherapy and radiation along with enteral feeding tube placement prior to/during treatment presented with acquired esophageal atresia. All patients underwent an EGD to reestablish lumenal patency. This was accomplished with gentle pressure that was applied in a to-and-fro semi-circular rotational manner as if pushing a corkscrew and twisting it in alternating clockwise and counterclockwise manner. RESULTS: In all cases we were able to reestablish esophageal lumenal patency with a single procedure. There were no adverse events. Four of the 5 patients required additional dilations for symptomatic management. However, all patients’ esophageal lumens remained patent. CONCLUSIONS: We describe a novel yet simple technique to treat acquired esophageal atresia after radiation for head and neck cancer. This technique allows for generous dilation yielding complete resolution of the stenosis in a single session. When our approach is used, the patient can be discharged home the same day and resume immediate oral intake. Elsevier 2022-09-20 /pmc/articles/PMC9718655/ /pubmed/36467535 http://dx.doi.org/10.1016/j.vgie.2022.08.003 Text en © 2022 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Video Case Series
Brindise, Elizabeth
Ashat, Munish
Gerke, Henning
El Abiad, Rami
A novel technique for the treatment of radiation-induced acquired esophageal atresia in patients with head and neck cancer
title A novel technique for the treatment of radiation-induced acquired esophageal atresia in patients with head and neck cancer
title_full A novel technique for the treatment of radiation-induced acquired esophageal atresia in patients with head and neck cancer
title_fullStr A novel technique for the treatment of radiation-induced acquired esophageal atresia in patients with head and neck cancer
title_full_unstemmed A novel technique for the treatment of radiation-induced acquired esophageal atresia in patients with head and neck cancer
title_short A novel technique for the treatment of radiation-induced acquired esophageal atresia in patients with head and neck cancer
title_sort novel technique for the treatment of radiation-induced acquired esophageal atresia in patients with head and neck cancer
topic Video Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718655/
https://www.ncbi.nlm.nih.gov/pubmed/36467535
http://dx.doi.org/10.1016/j.vgie.2022.08.003
work_keys_str_mv AT brindiseelizabeth anoveltechniqueforthetreatmentofradiationinducedacquiredesophagealatresiainpatientswithheadandneckcancer
AT ashatmunish anoveltechniqueforthetreatmentofradiationinducedacquiredesophagealatresiainpatientswithheadandneckcancer
AT gerkehenning anoveltechniqueforthetreatmentofradiationinducedacquiredesophagealatresiainpatientswithheadandneckcancer
AT elabiadrami anoveltechniqueforthetreatmentofradiationinducedacquiredesophagealatresiainpatientswithheadandneckcancer
AT brindiseelizabeth noveltechniqueforthetreatmentofradiationinducedacquiredesophagealatresiainpatientswithheadandneckcancer
AT ashatmunish noveltechniqueforthetreatmentofradiationinducedacquiredesophagealatresiainpatientswithheadandneckcancer
AT gerkehenning noveltechniqueforthetreatmentofradiationinducedacquiredesophagealatresiainpatientswithheadandneckcancer
AT elabiadrami noveltechniqueforthetreatmentofradiationinducedacquiredesophagealatresiainpatientswithheadandneckcancer