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Disease classification for whole-blood DNA methylation: Meta-analysis, missing values imputation, and XAI

BACKGROUND: DNA methylation has a significant effect on gene expression and can be associated with various diseases. Meta-analysis of available DNA methylation datasets requires development of a specific workflow for joint data processing. RESULTS: We propose a comprehensive approach of combined DNA...

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Detalles Bibliográficos
Autores principales:	Kalyakulina, Alena, Yusipov, Igor, Bacalini, Maria Giulia, Franceschi, Claudio, Vedunova, Maria, Ivanchenko, Mikhail
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718659/ https://www.ncbi.nlm.nih.gov/pubmed/36259657 http://dx.doi.org/10.1093/gigascience/giac097

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