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Reference panel guided topological structure annotation of Hi-C data

Accurately annotating topological structures (e.g., loops and topologically associating domains) from Hi-C data is critical for understanding the role of 3D genome organization in gene regulation. This is a challenging task, especially at high resolution, in part due to the limited sequencing covera...

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Detalles Bibliográficos
Autores principales: Zhang, Yanlin, Blanchette, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718747/
https://www.ncbi.nlm.nih.gov/pubmed/36460680
http://dx.doi.org/10.1038/s41467-022-35231-3